A complete blood count (CBC) is the most wide-spread laboratory test. The WBC differential count is a part of the CBC procedure. Despite high automation of laboratory tests, the WBC differential count is still performed manually. This part of the CBC requires particular attention, focus and highly qualified technologists.
Vision Hema Ultimate automates the differentiation of leucocytes and erythrocytes in blood smear. Load the slides into the cassette, insert it into the analyzer and the system will automatically perform white blood cell differentiation and morphological analysis of red blood cells. Final results will be presented in the form of cell images pre-classified into groups. The specialist only has to validate the results on a PC.
2 minutes per sample
Up to 30 samples per hour
Up to 700 samples per day
Up to 70 000 leucocytes and 350 000 erythrocytes per day
Comparison of automatic and manual blood smear analysis methods. Vision Hema Ultimate analyzes up to 700 blood smear samples in 24 hours. According to regulatory standards, manual WBC differential count of 1 smear takes 6 minutes. In other words, only 240 samples can be analyzed within the same time frame compared with the automatic method.
Vision Hema Ultimate automatically scans and analyzes blood smears. The specialist works with images of cells pre-classified into groups on PC monitor. Validation of 1 sample takes only 1 minute, which means the specialist examines 350 samples per shift. As a result, analysis of 700 blood smear samples only requires 1 workplace and 2 specialists that work in shifts.
A specialist manually examines approximately 80 samples per shift. The analysis is fully manual. Examination of 700 blood smear samples would require 3 workplaces and 9 specialists operating on a three-shift basis.
Vision Hema Ultimate performs blood smear analysis as defined by "Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods. CLSI H20-A2".
Each examined sample stores information about leucocyte’s collection path, detection control and quality control for differentiation of each type of leucocyte.
The system automatically calculates diagnostic sensitivity, specificity and efficiency for each type of leucocyte to evaluate quality control.
Quality control values are used for evaluation of leucocyte pre-classification accuracy. Diagnostic sensitivity (DSn), specificity (DSp) and efficiency (DE) are calculated as follows:
DSn = TP / (TP + FN)
Dsp = TN / (TN + FP)
DE = (TP + TN) / (TP + TN + FP + FN), where
TP — true positive, TN — true negative, FP — false positive, FN — false negative.
If the cell does not change its type (cell type 1) after validation, the result of its identification is considered true-positive (TP). If the cell does not change its type to cell type 1 after validation by the specialist, the result of its identification is considered true negative (TN).
If the cell is identified as cell type 1 but then changes its type, the result of its initial identification is considered false positive (FP). If the cell type is changed to cell type 1, the result of its identification is considered false negative (FN).
Vision Hema Ultimate shares a unified database with other Vision Hema systems. Medical institutions enhance cooperation with departments performing laboratory studies and improve the efficiency of the working process. Experts’ opinion for blood cells is available 24/7.
Vision Hema Remote software is intended for remote work with results. A sample analyzed in one medical institution may be reviewed in another. By using Vision Hema Remote pathologists and clinicians gain real time access to their patients’ cell images from their offices regardless of where the sample is analyzed.
The Vision Hema Ultimate enables bi-directional LIS communication that eliminates communication errors and simplifies transfer of results.
Appropriate workflow management during automated analysis of blood smear is ensured by multi-user access to the database with the flexible system of access rights settings. Each user’s action is registered in the log.
|Working modes||Blood smear analysis, virtual slide|
|Capacity||Up to 200 slides|
|Immersion oil dispensing||Automatic|
|Automatic scanning and pre-classification||Queue, continuous, random access, STAT testing, 24/7|
|Magnification||100x WBC, 50x RBC, 50x PLT|
|Quality control||Assessing diagnostic parameters: sensitivity, specificity and efficiency|
|Magnification||10x, 50x Oil, 100x Oil|
|Contents||Automatic slide loader
Built-in barcode reader
Microscope for scanning
Automatic oil dispenser
Touch-screen monitor for control
Monitor for validation
Vision Hema Ultimate software
Vision Hema Remote software
Instrument for preparation of blood smears
|Simultaneous loading||Up to 200 slides, 4 cassettes for 50 slides each|
|Supported codes||1D, 2D, QR|
|Optical system||100x Oil, 50x Oil, 10x|
|Microscopic slides||Standard 75x25 mm, 1.1 mm thick|
|Immersion oil||Automatic dispensing. A bottle of oil is enough for up to 1000 slides|
|Communication||Bi-directional LIS, LIS2-A2 (ASTM), Ethernet|
|Throughput||Up to 30 slides per hour (100 WBC, 500 RBC, PLT)|
|Multiple user access||4 preset types of users: Administrator, Doctor, Technician, Receptionist; new types of users can be added; adjustable access rights for users|
|Database||Multiple systems can share one database. 1 blood smear requires 2 MB and therefore 10 000 smears — 20 GB. Possibility to archive analysis results via transfer to external storage media|
|Modules||Vision Hema RTC — digital morphology of reticulocytes
Vision Hema Bone Marrow — count and study of bone marrow cells
Vision Hema Body Fluids — count and study of cells in human body fluids
|Remote access||Vision Hema Remote — remote access to blood smear analysis results|
|Equipment and accessories||Immersion oil
External barcode reader
Printer for barcode label printing
We invite you to visit West Medica’s office in Austria, where our specialists together with you can analyze your slides using Vision Hema Ultimate system. We will be happy to answer all your questions.
In case you are unable to visit us, feel free to send us your slides by post. We will provide an online broadcasting of the Vision Hema’s operation using the received blood smears. You will also have remote access to scanner control and analysis results.
We accept standard 75x25x1.1 mm slides.
To test Vision Hema Ultimate analyzer using your blood smear slides, send a request with the “Slides testing” box checked.